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Human CD3 Antibody : CY5

Product Specifications

CAS Number

9007-83-4

Gene Name

T-cell surface glycoprotein CD3 epsilon chain

Gene Aliases

T3E, TCRE, IMD18

Gene ID

916

Accession Number

NP_000724.1

Reactivity

Human

Immunogen

Human peripheral blood lymphocytes from a patient with Sezary's syndrome and infant thymocytes

Target

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Clonality

Monoclonal

Clone

UCHT1

Conjugation

Cyanine 5

Type

Monoclonal Antibody

Applications

FC, IHC-F, IHC-P, ICC, WB

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

Lot specific

Dilution

6 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells666666666

Reconstitution

Store at 2-8C

Notes

Formerly GWB-D02D66

Fragment

IgG1

Specificity

CD3

NCBI Gene Symbol

CD3E

Host or Source

Mouse

Protein Name

T-cell surface glycoprotein CD3 epsilon chain

Gene Name URL

CD3E

Nucleotide Accession Number

NM_000733.3

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