Human CD62E/E-selectin Antibody
Product Specifications
Gene Name
E-selectin
Gene Aliases
ELAM, ESEL, CD62E, ELAM1, LECAM2
Gene ID
6401; 6403; 397508
Accession Number
NP_000441.2
Reactivity
Human
Immunogen
TNF stimulated human endothelial cells
Target
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Clonality
Monoclonal
Clone
1.2B6
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
FC, IHC-F, ICC, IP, WB, BL
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.1 mg/mL
Dilution
6 cells
Fluorescein conjugate 10 uL/106 cells
BIOT conjugate 10 uL/106 cells
R-phycoerythrin conjugate 10 uL/106 cells
Allophycocyanin 10 uL/106 cells
Spectral Red conjugate 10 uL/106 cells66666
Reconstitution
Store at 2-8C
Notes
Formerly GWB-71ECDB
Fragment
IgG1
Specificity
CD62E/CD62P
NCBI Gene Symbol
SELE
Host or Source
Mouse
Protein Name
E-selectin
Gene Name URL
SELESELP
CAS Number
9007-83-4
Nucleotide Accession Number
NM_000450.2
Curated Selection
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