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Human CD62E/E-selectin Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

E-selectin

Gene Aliases

ELAM, ESEL, CD62E, ELAM1, LECAM2

Gene ID

6401; 6403; 397508

Accession Number

NP_000441.2

Reactivity

Human

Immunogen

TNF stimulated human endothelial cells

Target

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Clonality

Monoclonal

Clone

1.2B6

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

FC, IHC-F, ICC, IP, WB, BL

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.1 mg/mL

Dilution

6 cells Fluorescein conjugate 10 uL/106 cells BIOT conjugate 10 uL/106 cells R-phycoerythrin conjugate 10 uL/106 cells Allophycocyanin 10 uL/106 cells Spectral Red conjugate 10 uL/106 cells66666

Reconstitution

Store at 2-8C

Notes

Formerly GWB-71ECDB

Fragment

IgG1

Specificity

CD62E/CD62P

NCBI Gene Symbol

SELE

Host or Source

Mouse

Protein Name

E-selectin

Gene Name URL

SELESELP

Nucleotide Accession Number

NM_000450.2

Curated Selection

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