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Human CD11a/LFA-1a Antibody : Biotin

Product Specifications

CAS Number

9007-83-4

Gene Name

Integrin alpha-L

Gene Aliases

CD11A, LFA-1, LFA1A

Gene ID

3683

Accession Number

NP_001107852.1

Reactivity

Human

Immunogen

Fibronectin purified monocytes

Target

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Clonality

Monoclonal

Clone

38

Conjugation

Biotin

Type

Monoclonal Antibody

Applications

FC, IHC-F, IP

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

Lot specific

Dilution

6 cells 10 uL/106 cells 10 uL/106 cells 10 uL/106 cells666

Reconstitution

Store at 2-8C

Notes

Formerly GWB-E7CD5F

Fragment

IgG2a

Specificity

CD11a

NCBI Gene Symbol

ITGAL

Host or Source

Mouse

Protein Name

Integrin alpha-L

Gene Name URL

ITGAL

Nucleotide Accession Number

NM_001114380.1

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