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GFAP Antibody

Product Specifications

CAS Number

9007-83-4

Gene Aliases

ALXDRD

Gene ID

2670

Accession Number

NP_001124491.1

Reactivity

Bovine

Immunogen

Bovine spinal cord homogenate.

Target

It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell. Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death. Mouse anti Bovine GFAP antibody, clone 4A11 may be used in conjunction with Mouse anti Bovine GFAP antibody, clone 1B4 and Mouse anti Bovine GFAP antibody, clone 2E1 for increased sensitivity when used in immunohistology.

Clonality

Monoclonal

Clone

4A11

Type

Monoclonal Antibody

Applications

Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Radioimmunoassay|Western blot

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. Phosphate buffered saline

Reconstitution

-20°C

Notes

Formerly GWB-Q00835

Fragment

IgG2b

Specificity

Mouse anti Bovine GFAP antibody, clone 4A11 recognizes glial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells.

Host or Source

Mouse

Protein Name

Glial fibrillary acidic protein

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