GFAP Antibody
Product Specifications
CAS Number
9007-83-4
Gene Aliases
ALXDRD
Gene ID
2670
Accession Number
NP_001124491.1
Reactivity
Bovine
Immunogen
Bovine spinal cord homogenate.
Target
It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell. Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death. Mouse anti Bovine GFAP antibody, clone 4A11 may be used in conjunction with Mouse anti Bovine GFAP antibody, clone 1B4 and Mouse anti Bovine GFAP antibody, clone 2E1 for increased sensitivity when used in immunohistology.
Clonality
Monoclonal
Clone
4A11
Type
Monoclonal Antibody
Applications
Immunohistochemistry-Frozen|Immunohistochemistry-Paraffin|Radioimmunoassay|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. Phosphate buffered saline
Reconstitution
-20°C
Notes
Formerly GWB-Q00835
Fragment
IgG2b
Specificity
Mouse anti Bovine GFAP antibody, clone 4A11 recognizes glial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells.
Host or Source
Mouse
Protein Name
Glial fibrillary acidic protein
Curated Selection
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