Emr1 Antibody - Biotin Conjugated
Product Specifications
CAS Number
9007-83-4
Gene Aliases
Emr, Ly7, Emr1, Ly71, TM7L, F4/80, DD7A5-, Gpf480, TM7LN3, DD7A5-7, EGF-TM7
Gene ID
13733
Accession Number
NP_034260.1
Reactivity
Mouse
Immunogen
Thioglycollate stimulated peritoneal macrophages from C57BL/6 mice.
Target
Expression of F4/80 is heterogeneous and is modulated during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans cells, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 antigen is also expressed on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not been fully determined but a role for F4/80 in the generation of efferent CD8+ve regulatory T cells is proposed.
Clonality
Monoclonal
Clone
CI:A3-1
Conjugation
Biotin
Type
Monoclonal Antibody
Applications
Flow cytometry
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.1 mg/ml
Homology
Mouse
Format
Liquid. Phosphate buffered saline
Reconstitution
-20°C
Molecular Weight
160 kDa
Notes
Formerly GWB-Q01521
Fragment
IgG2b
Specificity
F4/80 ANTIGEN is a cell surface glycoprotein member of the EGF-TM7 family of proteins which shares 68% overall amino acid identity with human EGF module-containing mucin-like hormone receptor 1 (EMR1) .
Protein Length
931
NCBI Gene Symbol
EMR1
Host or Source
Rat
Protein Name
EGF-like module-containing mucin-like hormone receptor-like 1
Gene Name URL
Emr1
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items