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Emr1 Antibody - Biotin Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Aliases

Emr, Ly7, Emr1, Ly71, TM7L, F4/80, DD7A5-, Gpf480, TM7LN3, DD7A5-7, EGF-TM7

Gene ID

13733

Accession Number

NP_034260.1

Reactivity

Mouse

Immunogen

Thioglycollate stimulated peritoneal macrophages from C57BL/6 mice.

Target

Expression of F4/80 is heterogeneous and is modulated during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans cells, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 antigen is also expressed on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not been fully determined but a role for F4/80 in the generation of efferent CD8+ve regulatory T cells is proposed.

Clonality

Monoclonal

Clone

CI:A3-1

Conjugation

Biotin

Type

Monoclonal Antibody

Applications

Flow cytometry

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.1 mg/ml

Homology

Mouse

Format

Liquid. Phosphate buffered saline

Reconstitution

-20°C

Molecular Weight

160 kDa

Notes

Formerly GWB-Q01521

Fragment

IgG2b

Specificity

F4/80 ANTIGEN is a cell surface glycoprotein member of the EGF-TM7 family of proteins which shares 68% overall amino acid identity with human EGF module-containing mucin-like hormone receptor 1 (EMR1) .

Protein Length

931

NCBI Gene Symbol

EMR1

Host or Source

Rat

Protein Name

EGF-like module-containing mucin-like hormone receptor-like 1

Gene Name URL

Emr1

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