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Cd68 Antibody - Biotin Conjugated

Product Specifications

CAS Number

9007-83-4

Gene Aliases

La, ma, Sca, gp11, Lamp4, gp110, Scard1

Gene ID

12514

Accession Number

NP_033983.1

Reactivity

Mouse

Immunogen

Purified Concanavalin A acceptor glycoprotein from P815 cell line.

Target

Mouse macrosialin is a heavily glycosylated transmembrane protein and murine homolog of human CD68, which is classified as a unique scavenger recept (ScR) family member, due to the presence of a lysosome associated membrane protein (LAMP) -like domain. CD68 is considered a pan macrophage marker, predominantly expressed on the intracellular lysosomes of tissue macrophages/monocytes, including Kupffer cells, microglia, histiocytes and osteoclasts, and is expressed to a lesser extent by dendritic cells and peripheral blood granulocytes. CD68 is expressed by many tumor types including some B cell lymphomas, blastic NK lymphomas, melanomas, granulocytic (myeloid) sarcomas, hairy cell leukemias, and renal, urinary and pancreatic tumors, and can be used in cancer studies to demonstrate the presence/localization of macrophages.

Clonality

Monoclonal

Clone

FA-11

Conjugation

Biotin

Type

Monoclonal Antibody

Applications

Flow cytometry|Immunohistochemistry-Frozen

Purification

Protein G Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.1 mg/ml

Format

Liquid. Phosphate buffered saline

Reconstitution

-20°C

Notes

Formerly GWB-Q01481

Fragment

IgG2a

Specificity

CD68 (mouse macrosialin)

Protein Length

335

NCBI Gene Symbol

CD68

Host or Source

Rat

Protein Name

Macrosialin

Gene Name URL

Cd68

Frequently Asked Questions

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