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CRIP2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Epithelial splicing regulatory protein 1

Gene Aliases

2210008M09Rik; A630065D16; BC031468; epithelial splicing regulatory protein 1; Rbm3; Rbm35a; RNA binding motif protein 35A; RNA-binding motif protein 35A; RNA-binding protein 35A.

Gene ID

207920

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_918944.2

Reactivity

Mouse

Immunogen

Anti-Esrp-1 was produced by repeated immunizations of full length recombinant mouse Esrp-1 fusion protein.

Target

MRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT) . Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity) .

Clonality

Monoclonal

Clone

27H12.F3.H5

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Western blot

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Mouse

Format

Liquid (sterile filtered)

Reconstitution

-20°C|See manual

NCBI Gene Symbol

Esrp1

Host or Source

Mouse

Protein Name

Epithelial splicing regulatory protein 1|epithelial splicing regulatory protein 1 isoform 1 [Mus musculus]

Gene Name URL

Esrp1

Nucleotide Accession Number

NM_001270837.1NM_001270841.1NM_001312.3

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