TRPC6 Antibody
Product Specifications
Gene Name
Transient receptor potential cation channel subfamily C member 6
Gene Aliases
Focal segmental glomerulosclerosis 2; FSGS2; short transient receptor potential channel 6; transient receptor protein 6; TRP6; TRP-6.
Gene ID
7225
Accession Number
NP_004612.2
Reactivity
Human|Mouse
Immunogen
This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human TRPC6 protein.
Target
Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369) . Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346) . Seems not to be activated by intracellular calcium store depletion.
Clonality
Monoclonal
Clone
3F2.H10.F2
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human
Format
Liquid (sterile filtered)
Reconstitution
-20°C|See manual
NCBI Gene Symbol
TRPC6
Host or Source
Mouse
Protein Name
Short transient receptor potential channel 6
Gene Name URL
TRPC6
CAS Number
9007-83-4
Nucleotide Accession Number
NM_004621.5
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