Anti-Clavesin 1/2
Product Specifications
CAS Number
9007-83-4
Gene Aliases
Rlbp1l1, Clavesin-1, RGD1564200
Gene ID
366311
Accession Number
NP_001102439.1
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide taken from the C-terminus of rat clavesin 1.
Target
Clavesin (clathrin vesicle associated Sec14 protein) is a novel neuron specific protein that has recently been identified and shown to be required for normal morphology of late endosomes and/or lysosomes as lentiviral-mediated knockdown of clavesin in hippocampal neurons causes lysosomal defects (Katoh et al., 2009) . Additionally, upregulation of clavesin in human hepatocellular carcinoma has recently been demonstrated thus making it a useful marker for this disease state (Zhao et al., 2008) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, ICC
Purification
Prepared from serum by affinity purification using a column to which the peptide antigen was coupled.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Homology
Human; Mouse; Rat
Format
Liquid. 100 ul in PBS + 50% glycerol.
Reconstitution
Store at -20C in undiluted aliquots; stable for up at least 1 year after date of receipt. Avoid freeze/thaw cycles.
Molecular Weight
~35kDa
Specificity
Specific for the ~ 35 kDa clavesin 1/2 protein doublet in Western blots of rat brain lysate. Isoform-specific knock down in cultured hippocampal neurons indicates that the lower and upper bands are clavesin 1 and 2, respectively.
NCBI Gene Symbol
CLVS1/2
Host or Source
Rabbit
Protein Name
Clavesin-1
Gene Name URL
CLVS1/2
Frequently Asked Questions
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