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MKRN3 Antibody - C-terminal

Product Specifications

CAS Number

9007-83-4

Gene Name

Makorin ring finger protein 3

Gene Aliases

CPPB2; D15S9; probable E3 ubiquitin-protein ligase makorin-3; RING finger protein 63; RING-type E3 ubiquitin transferase makorin-3; RNF63; ZFP127; zinc finger protein 127; ZNF127.

Gene ID

7681

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_005655

Reactivity

Human|Mouse|Rat

Immunogen

MKRN3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MKRN3. The immunogen is located within amino acids 400 - 450 of MKRN3.

Target

The Makorin ring finger 3 (MKRN3) protein contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. The MKRN3 gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome (1), but a deletion of the gene does not (2) . A deficiency of MKRN3 has been shown to cause central precocious puberty in humans (3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. MKRN3 antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

Predicted: 55 kDa Observed: 55 kDa

Fragment

IgG

NCBI Gene Symbol

MKRN3

Host or Source

Rabbit

Protein Name

MKRN3 protein|probable E3 ubiquitin-protein ligase makorin-3 [Homo sapiens]

Gene Name URL

MKRN3

Nucleotide Accession Number

NM_005664.3

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