NLGN2 Antibody - C-terminal
Product Specifications
CAS Number
9007-83-4
Gene Name
Neuroligin 2
Gene Aliases
Neuroligin-2.
Gene ID
57555
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_065846
Reactivity
Human|Mouse|Rat
Immunogen
NLGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NLGN2. The immunogen is located within amino acids 630 - 680 of NLGN2.
Target
Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA (A) receptors) . Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing. Required for normal signal amplitude from inhibitory synapses, but is not essential for normal signal frequency. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. Mediates cell-cell interactions between Langerhans beta cells and modulates insulin secretion (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. NLGN2 antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
Predicted: 92, 99 kDa Observed: 80, 97 kDa
Fragment
IgG
NCBI Gene Symbol
NLGN2
Host or Source
Rabbit
Protein Name
Neuroligin-2|neuroligin-2 precursor [Homo sapiens]
Gene Name URL
NLGN2
Nucleotide Accession Number
NM_020795.3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
212751-01 20 µL
PPP6C (Protein Phosphatase 6, Catalytic Subunit, PP6, PP6C) discontinued
Sign In for Pricing
View Details 212751-02 100 µL
PPP6C (Protein Phosphatase 6, Catalytic Subunit, PP6, PP6C) discontinued
Sign In for Pricing
View Details 
MBS6157453-01 0.1 mL
DIO1 (Type I Iodothyronine Deiodinase, Type-I 5'-deiodinase, Type 1 DI, DIOI, 5DI, TXDI1, ITDI1) (PE)
Sign In for Pricing
View Details MBS6157453-02 5x 0.1 mL
DIO1 (Type I Iodothyronine Deiodinase, Type-I 5'-deiodinase, Type 1 DI, DIOI, 5DI, TXDI1, ITDI1) (PE)
Sign In for Pricing
View Details