SREBF2 Antibody - N-terminal
Product Specifications
CAS Number
9007-83-4
Gene Name
Sterol regulatory element binding transcription factor 2
Gene Aliases
BHLHd2; class D basic helix-loop-helix protein 2; SREBP2; SREBP-2; sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2.
Gene ID
6721
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_004590
Reactivity
Human|Mouse|Rat
Immunogen
SREBF2 antibody was raised against a 15 amino acid peptide near the center of human SREBF2. The immunogen is located within amino acids 440 - 490 of SREBF2.
Target
Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway (By similarity) . Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. SREBF2 antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
Predicted: 126 kDa Observed: 128 kDa
Fragment
IgG
NCBI Gene Symbol
SREBF2
Host or Source
Rabbit
Protein Name
Sterol regulatory element-binding protein 2|sterol regulatory element-binding protein 2 [Homo sapiens]
Gene Name URL
SREBF2
Nucleotide Accession Number
NM_004599.3
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