PD 123177

PD 123177 is a nonpeptide antagonist specific for angiotensin II (AII) subtype AT2 receptor in mammalian systems[1].

Product Specifications

CAS Number

[114785-12-5]

UNSPSC

12352005

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pd-123177.html

Purity

98.14

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(O)C1CC2=C(CN1C(C(C3=CC=CC=C3)C4=CC=CC=C4)=O)N=CN2CC5=CC=C(C(C)=C5)N

Molecular Formula

C29H28N4O3

Molecular Weight

480.56

References & Citations

[1]C S Cobb, et al. Characterization of putative glomerular receptors for angiotensin II in the rainbow trout Oncorhynchus mykiss using the antagonists Losartan, PD 123177, and saralasin. Gen Comp Endocrinol. 1993 Oct;92 (1) :123-31.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AT2 Receptor

Available Sizes

Curated Selection

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