PD 123177
PD 123177 is a nonpeptide antagonist specific for angiotensin II (AII) subtype AT2 receptor in mammalian systems[1].
Product Specifications
CAS Number
114785-12-5
UNSPSC
12352005
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/pd-123177.html
Purity
98.14
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C1CC2=C(CN1C(C(C3=CC=CC=C3)C4=CC=CC=C4)=O)N=CN2CC5=CC=C(C(C)=C5)N
Molecular Formula
C29H28N4O3
Molecular Weight
480.56
References & Citations
[1]C S Cobb, et al. Characterization of putative glomerular receptors for angiotensin II in the rainbow trout Oncorhynchus mykiss using the antagonists Losartan, PD 123177, and saralasin. Gen Comp Endocrinol. 1993 Oct;92 (1) :123-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AT2 Receptor
Available Sizes
Frequently Asked Questions
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