ME1 Antibody - N-terminal

HUMNDME; malate dehydrogenase (oxaloacetate-decarboxylating) (NADP (+) ) ; Malic enzyme 1; malic enzyme 1, NADP (+) -dependent, cytosolic; malic enzyme 1, soluble; Malic enzyme, cytoplasmic; MES; NADP-dependent malic enzyme; NADP-ME; pyruvic-malic carboxylase.

ME1 antibody was raised against a 16 amino acid peptide near the amino terminus of human ME1. The immunogen is located within the first 50 amino acids of ME1.

ME1, also known as NADP-ME, MES or HUMNDME, may play an important role as a housekeeping protein within the cell (1) . ME1 is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family (2) . It is expressed ubiquitously with highest expression in liver and white adipose tissue. ME1 functions as an NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (3) . The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles (3,4) . ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet (5) .

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol