LAMTOR2 Antibody - N-terminal

ENDAP; endosomal adaptor protein p14; HSPC003; late endosomal/lysosomal adaptor and MAPK and MTOR activator 2; late endosomal/lysosomal Mp1-interacting protein; MAPBP-interacting protein; MAPBPIP; MAPKSP1 adaptor protein; MAPKSP1AP; Mitogen-activated protein-binding protein-interacting protein; mitogen-activated protein-binding protein-interacting protein (MAPBPIP) ; p14; ragulator complex protein LAMTOR2; Ragulator2; roadblock domain containing 3; roadblock domain-containing protein 3; ROBLD3.

LAMTOR2 antibody was raised against an 18 amino acid peptide near the center of human LAMTOR2. The immunogen is located within amino acids 40 - 90 of LAMTOR2.

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol