TLX3 Antibody - N-terminal
Product Specifications
CAS Number
9007-83-4
Gene Name
T cell leukemia homeobox 3
Gene Aliases
Homeo box 11-like 2; homeobox protein Hox-11L2; HOX11L2; RNX; T-cell leukemia homeobox protein 3.
Gene ID
30012
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_066305
Reactivity
Human|Mouse|Rat
Immunogen
TLX3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TLX3. The immunogen is located within the first 50 amino acids of TLX3.
Target
TLX3 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX3, also known as homeobox11-like1 (HOX11L2), is a DNA-binding nuclear transcription factor that is expressed in a subset of the primary sensory nervous system. TLX3, along with the related TLX1, is a selector transcription factor that promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype opposing LBX1 signals during dorsal spinal cord development. Chromosomal translocations of the TLX3 gene have been shown to result in some forms of T-cell acute lymphoblastic leukemia (T-ALL) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. TLX3 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
2°C to 8°C
Molecular Weight
Predicted: 32 kDa Observed: 30 kDa
Fragment
IgG
NCBI Gene Symbol
TLX3
Host or Source
Rabbit
Protein Name
T-cell leukemia homeobox protein 3|T-cell leukemia homeobox protein 3 [Homo sapiens]
Gene Name URL
TLX3
Nucleotide Accession Number
NM_021025.3
Curated Selection
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