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GBP5 Antibody - C-terminal

Product Specifications

Gene Name

Guanylate binding protein 5

Gene Aliases

GBP-5; GBP-TA antigen; GTP-binding protein 5; guanine nucleotide-binding protein 5; guanylate-binding protein 5.

Gene ID

115362

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_443174

Reactivity

Human|Mouse|Rat

Immunogen

GBP5 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GBP5 . The immunogen is located within the last 50 amino acids of GBP5.

Target

As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501) . Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. GBP5 Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Molecular Weight

Predicted: 64 kDa Observed: 66 kDa

Fragment

IgG

NCBI Gene Symbol

GBP5

Host or Source

Rabbit

Protein Name

Guanylate-binding protein 5|guanylate-binding protein 5 [Homo sapiens]

Gene Name URL

GBP5

CAS Number

9007-83-4

Nucleotide Accession Number

NM_001134486.2

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