TSC22D3 Antibody - N-terminal
Product Specifications
CAS Number
9007-83-4
Gene Name
TSC22 domain family member 3
Gene Aliases
Delta sleep-inducing peptide immunoreactor; DIP; DSIPI; DSIP-immunoreactive leucine zipper protein; DSIP-immunoreactive peptide; GILZ; glucocorticoid-induced leucine zipper protein; TSC22 domain family protein 3; TSC-22 related protein; TSC-22-like protein; TSC-22R; TSC-22-related protein.
Gene ID
1831
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_932174
Reactivity
Human|Mouse
Immunogen
Rabbit polyclonal TSC22D3 antibody was raised against a 16 amino acid peptide near the amino terminus of human TSC22D3. The immunogen is located within amino acids 40 - 90 of TSC22D3.
Target
Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity) . Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. TSC22D3 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
Predicted: 22 kDa Observed: 23 kDa
Fragment
IgG
NCBI Gene Symbol
TSC22D3
Host or Source
Rabbit
Protein Name
TSC22 domain family protein 3|TSC22 domain family protein 3 isoform 1 [Homo sapiens]
Gene Name URL
TSC22D3
Nucleotide Accession Number
NM_001015881.1
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