TFCP2L1 Antibody - N-terminal
Product Specifications
CAS Number
9007-83-4
Gene Name
Transcription factor CP2 like 1
Gene Aliases
CP2-related transcriptional repressor 1; CRTR1; CRTR-1; LBP9; LBP-9; transcription factor CP2-like protein 1; transcription factor LBP-9.
Gene ID
29842
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_055368
Reactivity
Human|Mouse|Rat
Immunogen
TFCP2L1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human TFCP2L1. The immunogen is located within the first 50 amino acids of TFCP2L1.
Target
Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (PubMed:25215486, PubMed:26906118) . With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity) . Required for normal duct development in the salivary gland and kidney (By similarity) . Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity) . Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity) . Regulates also the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity) . JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity) . Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity) . Modulates the placental expression of CYP11A1 (PubMed:10644752) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid. TFCP2L1 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Fragment
IgG
NCBI Gene Symbol
TFCP2L1
Host or Source
Rabbit
Protein Name
Transcription factor CP2-like protein 1|transcription factor CP2-like protein 1 [Homo sapiens]
Gene Name URL
TFCP2L1
Nucleotide Accession Number
NM_014553.2
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K3289302 1.0 µg DNA
Serpinb13 sgRNA CRISPR Lentivector (Mouse) (Target 1)
Sign In for Pricing
View Details 
MBS6452875-01 0.1 mL
Nanog (Homeobox Protein NANOG, ENK, Embryonic Stem Cell Specific Homeobox Protein, Homeobox Transcription Factor Nanog) (Biotin)
Sign In for Pricing
View Details MBS6452875-02 5x 0.1 mL
Nanog (Homeobox Protein NANOG, ENK, Embryonic Stem Cell Specific Homeobox Protein, Homeobox Transcription Factor Nanog) (Biotin)
Sign In for Pricing
View Details