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LEMD1 Antibody - N-terminal

Product Specifications

CAS Number

9007-83-4

Gene Name

LEM domain containing 1

Gene Aliases

Cancer/testis antigen 50; CT50; LEM domain protein 1; LEM domain-containing protein 1; LEMP-1.

Gene ID

93273

Reactivity

Human|Mouse

Immunogen

LEMD1 antibody was raised against a 19 amino acid synthetic peptide near the center of human LEMD1. The immunogen is located within amino acids 90 - 140 of LEMD1.

Target

LEMD1 (LEM domain-containing1) is a member of cancer-testis gene family. LEMD1 is normally expressed only in testis. Six alternatively spliced forms of LEMD1 transcripts in normal testis have been identified, but only one of the six was expressed in colorectal cancers. LEMD1 may represent a promising target antigen for immunotherapy of colorectal cancers. In addition, LEMD1 and SPATA19 are putative cancer biomarkers and promising targets for active immunotherapy.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. LEMD1 Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

For short term use, store at 2-8C for up to three months. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles (stable for up to one year) . Antibodies should not be exposed to prolonged high temperatures.

Fragment

IgG

Specificity

At least six isoforms of LEMD1 are known to exist; this antibody will detect the longest isoform. LEMD1 antibody is predicted to not cross-react with LEMD2 and LEMD3.

NCBI Gene Symbol

LEMD1

Host or Source

Rabbit

Protein Name

LEM domain-containing protein 1

Gene Name URL

LEMD1

Nucleotide Accession Number

NM_001001552.4

Frequently Asked Questions

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