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ZNF521 Antibody - C-terminal

Product Specifications

CAS Number

9007-83-4

Gene Name

Zinc finger protein 521

Gene Aliases

Early hematopoietic zinc finger protein; EHZF; Evi3; LYST-interacting protein 3; zinc finger protein 521.

Gene ID

25925

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_056276

Reactivity

Human|Mouse

Immunogen

ZNF521 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ZNF521. The immunogen is located within amino acids 1160 - 1210 of ZNF521.

Target

Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. ZNF521 Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

Fragment

IgG

NCBI Gene Symbol

ZNF521

Host or Source

Rabbit

Protein Name

Zinc finger protein 521|zinc finger protein 521 isoform 1 [Homo sapiens]

Gene Name URL

ZNF521

Nucleotide Accession Number

NM_001308225.1

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