MD-2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Lymphocyte antigen 96

Gene Aliases

ESOP-1; ly-96; lymphocyte antigen 96; MD2; MD-2; myeloid differentiation protein-2; protein MD-2.

Gene ID

23643

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_056179

Reactivity

Human|Mouse

Immunogen

Mouse monoclonal MD-2 antibody was raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2.

Target

Binds bacterial lipopolysaccharide (LPS) (PubMed:17803912, PubMed:17569869) . Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria (PubMed:11160242, PubMed:11593030) . Enhances TLR4-dependent activation of NF-kappa-B (PubMed:10359581) . Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS (PubMed:10359581) .

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

Purification

Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol