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Apaf-1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Apoptotic peptidase activating factor 1

Gene Aliases

APAF-1; apoptotic protease-activating factor 1; CED4.

Gene ID

317

Accession Number

https://www.ncbi.nlm.nih.gov/protein/AAC51678

Reactivity

Human|Mouse|Rat

Immunogen

A peptide corresponding to amino acids near the carboxy terminus of human Apaf1.

Target

Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Clonality

Monoclonal

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. Apaf-1 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

Apaf-1 monoclonal antibody can be stored at 4C, stable for one year.

Molecular Weight

130 kDa

NCBI Gene Symbol

APAF1

Protein Name

Apoptotic protease activating factor 1 [Homo sapiens]|Apoptotic protease-activating factor 1

Gene Name URL

APAF1

Frequently Asked Questions

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