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TNIP3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

TNFAIP3 interacting protein 3

Gene Aliases

A20-binding inhibitor of NF-kappa-B activation 3; ABIN-3; ABIN-3 beta; LIND; Listeria induced; listeria-induced gene protein; TNFAIP3-interacting protein 3; TNFAIP3-interacting protein 3 beta; TNIP3 beta.

Gene ID

79931

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_079149

Reactivity

Human|Mouse

Immunogen

ABIN3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ABIN3. The immunogen is located within the last 50 amino acids of ABIN3.

Target

Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Human; Mouse

Format

Liquid. ABIN3 Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

ABIN3 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

NCBI Gene Symbol

TNIP3

Host or Source

Rabbit

Protein Name

TNFAIP3-interacting protein 3|TNFAIP3-interacting protein 3 isoform 1 [Homo sapiens]

Gene Name URL

TNIP3

Nucleotide Accession Number

NM_001128843.2NM_001244764.1NM_024873.5

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