What is the catalog number for KLHL15 Antibody?

The catalog number for KLHL15 Antibody is OAPB00907-100UG.

What sizes are available for KLHL15 Antibody?

KLHL15 Antibody is available in the following size(s): 0.1 mg.

Is KLHL15 Antibody in stock?

KLHL15 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

KLHL15 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Kelch like family member 15

Gene Aliases

Epididymis secretory protein Li 305; epididymis secretory sperm binding protein; HEL-S-305; kelch-like 15; kelch-like protein 15; XLID103.

Gene ID

80311

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_085127

Reactivity

Human|Mouse|Rat

Immunogen

KLHL15 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human KLHL15. The immunogen is located within the last 50 amino acids of KLHL15.

Target

Substrate-specific adapter for CUL3 E3 ubiquitin-protein ligase complex (PubMed:14528312) . Acts as an adapter for CUL3 to target the serine/threonine-protein phosphatase 2A (PP2A) subunit PPP2R5B for ubiquitination and subsequent proteasomal degradation, thus promoting exchange with other regulatory subunits (PubMed:23135275) . Acts as an adapter for CUL3 to target the DNA-end resection factor RBBP8/CtIP for ubiquitination and subsequent proteasomal degradation. Through the regulation of RBBP8/CtIP protein turnover, plays a key role in DNA damage response, favoring DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR) (PubMed:27561354) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. KLHL15 Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

KLHL15 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.