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FNIP2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Folliculin interacting protein 2

Gene Aliases

FNIP1-like protein; FNIPL; folliculin-interacting protein 2; MAPO1; O6-methylguanine-induced apoptosis 1 protein.

Gene ID

57600

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_065891

Reactivity

Human|Mouse|Rat

Immunogen

FNIP2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human FNIP2. The immunogen is located within amino acids 860 - 910 of FNIP2.

Target

Acts as a co-chaperone of HSP90AA1. Inhibits the ATPase activity of HSP90AA1 leading to reduction in its chaperone activity. Facilitates the binding of client protein FLCN to HSP90AA1 (PubMed:27353360) . May play a role in the signal transduction pathway of apoptosis induced by O6-methylguanine-mispaired lesions (By similarity) . May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways (PubMed:18403135) . May regulate phosphorylation of RPS6KB1 (PubMed:18663353) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. FNIP2 Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

FNIP2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

NCBI Gene Symbol

FNIP2

Host or Source

Rabbit

Protein Name

Folliculin-interacting protein 2|folliculin-interacting protein 2 isoform 1 [Homo sapiens]

Gene Name URL

FNIP2

Nucleotide Accession Number

NM_020840.1XM_005263159.1

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