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Fermt3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

FERM domain containing kindlin 3

Gene Aliases

Fermitin family homolog 3; fermitin family member 3; KIND3; kindlin 3; Kindlin-3; MIG-2; MIG2B; MIG2-like protein; UNC-112 related protein 2; UNC112C; unc-112-related protein 2; URP2; URP2SF.

Gene ID

83706

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_848537

Reactivity

Bovine|Human|Mouse|Rat

Immunogen

KINDLIN3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of the human KINDLIN3. The immunogen is located within the last 50 amino acids of KINDLIN3.

Target

Plays a central role in cell adhesion in hematopoietic cells (PubMed:19234463, PubMed:26359933) . Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (By similarity) . Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234460) . Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. KINDLIN3 Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

KINDLIN3 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Molecular Weight

Predicted: 73 kDa Observed: 73 kDa

NCBI Gene Symbol

FERMT3

Host or Source

Rabbit

Protein Name

Fermitin family homolog 3|fermitin family homolog 3 long form [Homo sapiens]

Gene Name URL

FERMT3

Nucleotide Accession Number

NM_153795.2XM_006526593.2

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