Slc22A17 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Solute carrier family 22 member 17
Gene Aliases
24p3 receptor;24p3R; BOCT; BOIT; brain-type organic cation transporter; hBOIT; lipocalin-2 receptor; neutrophil gelatinase-associated lipocalin receptor; NGAL receptor; NGALR; NGALR2; NGALR3; potent brain type organic ion transporter; solute carrier family 22 (organic cation transporter), member 17; solute carrier family 22 member 17.
Gene ID
51310
Reactivity
Bovine|Human|Mouse|Rat
Immunogen
Slc22A17 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of the human Slc22A17. The immunogen is located within the last 50 amino acids of Slc22A17.
Target
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat
Format
Liquid. Slc22A17 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
Slc22A17 antibody can be stored at 4C for three months. 20C for up to a year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
Predicted: 59 kDa Observed: 61 kDa
Fragment
IgG
NCBI Gene Symbol
SLC22A17
Host or Source
Rabbit
Protein Name
Solute carrier family 22 member 17
Gene Name URL
SLC22A17
Frequently Asked Questions
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