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TLR9 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Toll like receptor 9

Gene Aliases

CD289; toll-like receptor 9.

Gene ID

54106

Accession Number

https://www.ncbi.nlm.nih.gov/protein/AAH32713

Reactivity

Human|Mouse|Rat

Immunogen

TLR9 antibody was raised against a peptide corresponding to 15 amino acids near the center of human TLR9. The immunogen is located within amino acids 840 - 890 of TLR9.

Target

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:11564765, PubMed:17932028) . Controls lymphocyte response to Helicobacter infection (By similarity) . Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (PubMed:23857366) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. TLR9 Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

2°C to 8°C

Molecular Weight

Predicted: 104, 111 kDa Observed: 97 kDa

NCBI Gene Symbol

TLR9

Host or Source

Rabbit

Protein Name

Toll-like receptor 9|Toll-like receptor 9 [Homo sapiens]

Gene Name URL

TLR9

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