Adiponectin Antibody
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Product Specifications
CAS Number
9007-83-4
Gene Name
Adiponectin, C1Q and collagen domain containing
Gene Aliases
30 kDa adipocyte complement-related protein; ACDC; ACRP30; adipocyte complement-related 30 kDa protein; Adipocyte, C1q and collagen domain-containing protein; adiponectin; adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; ADIPQTL1; ADPN; APM1; APM-1; GBP28; Gelatin-binding protein; gelatin-binding protein 28.
Gene ID
9370
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_004788
Reactivity
Bovine|Human|Mouse|Rat
Immunogen
Adiponectin antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human adiponectin. The immunogen is located within the last 50 amino acids of Adiponectin.
Target
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse; Rat, Bovine (71%)
Format
Liquid. Adiponectin Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
Adiponectin antibody can be stored at 4C for three months and -20C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
Predicted: 27 kDa Observed: 26 kDa
Fragment
IgG
NCBI Gene Symbol
ADIPOQ
Host or Source
Rabbit
Protein Name
Adiponectin|adiponectin precursor [Homo sapiens]
Gene Name URL
ADIPOQ
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