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West Nile Virus Core Antibody

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Product Specifications

CAS Number

9007-83-4

Gene Name

Polyprotein; truncated polyprotein NS1 prime

Gene Aliases

Polyprotein; truncated polyprotein NS1 prime; WNVgp1.

Gene ID

912267

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_776011

Reactivity

Virus|West Nile Virus

Immunogen

West Nile Virus Core antibody was raised against a synthetic peptide corresponding to 15 amino acids near the carboxy terminus of the West Nile Virus core protein. The immunogen is located within amino acids 80 - 130 of West Nile Virus Core.

Target

Capsid protein C: Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle (By similarity) . During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins (By similarity) . Can migrate to the cell nucleus where it modulates host functions (By similarity) . Overcomes the anti-viral effects of host EXOC1 by sequestering and degrading the latter through the proteasome degradation pathway (PubMed:23522008) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunocytochemistry|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Virus

Format

Liquid. West Nile Virus Core Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

West Nile Virus Core antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

NCBI Gene Symbol

POLY

Host or Source

Rabbit

Protein Name

Genome polyprotein|unnamed protein product [West Nile virus]

Gene Name URL

POLY

Nucleotide Accession Number

NC_001563.2

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