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TIRAP Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

TIR domain containing adaptor protein

Gene Aliases

Adapter protein wyatt; adaptor protein Wyatt; BACTS1; Mal; MyD88 adapter-like protein; MyD88-2; toll/interleukin-1 receptor domain-containing adapter protein; toll-interleukin 1 receptor (TIR) domain containing adaptor protein; Toll-like receptor adaptor protein; wyatt.

Gene ID

114609

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_473437

Reactivity

Human|Mouse|Rat

Immunogen

TIRAP antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of mouse TIRAP. The immunogen is located within the last 50 amino acids of TIRAP.

Target

Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. TIRAP Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

TIRAP antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Molecular Weight

Predicted: 24, 26 kDa Observed: 24 kDa

Notes

Formerly GWB-F1205B

NCBI Gene Symbol

TIRAP

Host or Source

Rabbit

Protein Name

Toll/interleukin-1 receptor domain-containing adapter protein|toll/interleukin-1 receptor domain-containing adapter protein [Mus musculus]

Gene Name URL

TIRAP

Nucleotide Accession Number

NM_001039661.1NM_148910.2

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