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ANP32E Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Acidic nuclear phosphoprotein 32 family member E

Gene Aliases

Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E; acidic leucine-rich nuclear phosphoprotein 32 family member E; LANPL; LANP-L; LANP-like protein; leucine-rich acidic nuclear protein like.

Gene ID

81611

Accession Number

https://www.ncbi.nlm.nih.gov/protein/NP_112182

Reactivity

Human|Mouse|Rat

Immunogen

PHAP III antibody was raised with a synthetic peptide corresponding to amino acids close to carboxy terminus of human PHAP III. The immunogen is located within amino acids 200 - 250 of PHAP III.

Target

Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511) . Inhibits activity of protein phosphatase 2A (PP2A) . Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. PHAP III Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

2°C to 8°C

Molecular Weight

35 kDa

Notes

Formerly GWB-6655D6

Fragment

IgG

Specificity

PHAP III has no cross-reaction to PHAP I and PHAP I2a.

NCBI Gene Symbol

ANP32E

Host or Source

Rabbit

Protein Name

Acidic leucine-rich nuclear phosphoprotein 32 family member E|acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1 [Homo sapiens]

Gene Name URL

ANP32E

Nucleotide Accession Number

NM_001136478.3NM_001136479.2NM_001280559.1NM_001280560.1NM_030920.4

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