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DcR1 Antibody

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Product Specifications

CAS Number

9007-83-4

Gene Name

TNF receptor superfamily member 10c

Gene Aliases

Antagonist decoy receptor for TRAIL/Apo-2L; CD263; cytotoxic TRAIL receptor-3; DCR1; DCR1-TNFR; decoy receptor 1; decoy TRAIL receptor without death domain; LIT; lymphocyte inhibitor of TRAIL; TNF-related apoptosis-inducing ligand receptor 3; TRAIL receptor without an intracellular domain; TRAILR3; TRAIL-R3; TRID; tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain.

Gene ID

8794

Accession Number

AF012536

Reactivity

Human|Mouse|Rat

Immunogen

DcR1 antibody was raised against a peptide corresponding to amino acids in a extracellular domain of human DcR1 precursor. The immunogen is located within amino acids 140 - 190 of DcR1.

Target

Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Homology

Human; Mouse; Rat

Format

Liquid. DcR1 Antibody is supplied in PBS containing 0.02% sodium azide.

Reconstitution

DcR1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Molecular Weight

65 kDa

Notes

Formerly GWB-409B26

NCBI Gene Symbol

TNFRSF10C

Host or Source

Rabbit

Protein Name

Homo sapiens decoy receptor 1 (DcR1) mRNA, complete cds|Tumor necrosis factor receptor superfamily member 10C

Gene Name URL

TNFRSF10C

Nucleotide Accession Number

https://www.ncbi.nlm.nih.gov/nuccore/AF012536

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