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PLP Antibody

Product Specifications

CAS Number

9007-83-4

Gene Aliases

PLP, PMD, HLD1, MMPL, SPG2, GPM6C, PLP/DM20

Gene ID

5354

Immunogen

S_x005F ynthetic pPLP 139-151.

Target

Lipophilin is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. PLP functions in myelination. plays a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations associated with PLP gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Two transcript variants encoding distinct isoforms have been identified for PLP gene.PLP is the major myelin protein from the central nervous system and plays an important role in the formation or maintenance of the multilamellar structure of myelin.

Clonality

Monoclonal

Clone

NYRPLP.

Type

Monoclonal Antibody

Applications

WB, IP, IHC

Purification

Ion exchange column.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Lyophilized.

Reconstitution

Shipping Conditions: //Antibody is shipped lyophilized at ambient temperature.

Notes

Formerly GWB-F03E95

Fragment

Mouse IgG1.

NCBI Gene Symbol

PLP1

Host or Source

Mouse

Protein Name

Myelin proteolipid protein

Gene Name URL

PLP1

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