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C6 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Aliases

C6, Complement component C6, Complement C6, Complement component 6

Gene ID

729

Accession Number

NP_000056.2

Reactivity

Human

Immunogen

Purified human C6

Clonality

Monoclonal

Epitope

C-Terminus

Clone

056B-214.2.4.2

Conjugation

Unconjugated

Type

Monoclonal Antibody

Applications

ELISA, FC, IHC, IHC-P

Purification

Protein A purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid

Buffer

BBS, 0.1% Sodium Azide

Reconstitution

Store at 4C or at -20C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

Fragment

IgG1

Specificity

Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC) . Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.

Formulation

0

NCBI Gene Symbol

C6

Host or Source

Mouse

Gene Name URL

C6

Nucleotide Accession Number

NM_000065

Frequently Asked Questions

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