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XRCC6 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

X-ray repair cross complementing 6

Gene Aliases

ML8, KU70, TLAA, CTC75, CTCBF, G22P1

Gene ID

2547

Accession Number

NP_001275905.1

Reactivity

Human

Immunogen

Recombinant antigen containing the amino terminal portion of human Ku70 protein

Target

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Clonality

Monoclonal

Clone

529

Type

Monoclonal Antibody

Applications

ICC, IF, WB

Purification

Protein G purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid

Buffer

Phosphate-buffered saline, pH 7.2, containing no preservatives

Reconstitution

Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

Fragment

IgG

NCBI Gene Symbol

XRCC6

Host or Source

Mouse

Protein Name

X-ray repair cross-complementing protein 6

Gene Name URL

XRCC6

Nucleotide Accession Number

NM_001288976.1

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