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RBBP4 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

RB binding protein 4, chromatin remodeling factor

Gene Aliases

NURF55, RBAP48, lin-53

Gene ID

5928

Accession Number

NP_001128727.1

Reactivity

Human, Mouse

Immunogen

The complete coding region (amino acids 1-425) of RbAp48 expressed in E. coli.

Target

This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.

Clonality

Monoclonal

Clone

15G12

Type

Monoclonal Antibody

Applications

ICC, IF, IHC-P, IP, WB

Purification

Protein G purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid

Buffer

Phosphate-buffered saline, pH 7.4, containing no preservatives

Reconstitution

Keep as concentrated solution. Store at 4C short term. For extended storage aliquot and store at -20C or below. Avoid freeze-thaw cycles.

Fragment

IgG2a

NCBI Gene Symbol

RBBP4

Host or Source

Mouse

Protein Name

Histone-binding protein RBBP4

Gene Name URL

RBBP4

Nucleotide Accession Number

NM_001135255.1

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