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PUF60 Antibody

Product Specifications

Gene Name

Poly (U) binding splicing factor 60

Gene Aliases

FIR, VRJS, RoBPI, SIAHBP1

Gene ID

22827

Accession Number

NP_001129505.1

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein encompassing a sequence within the center region of human PUF60. The exact sequence is proprietary.

Target

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Clonality

Monoclonal

Clone

GT917

Type

Monoclonal Antibody

Applications

WB

Purification

Affinity purified by Protein G.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid

Buffer

PBS

Reconstitution

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Fragment

IgG2b

NCBI Gene Symbol

PUF60

Host or Source

Mouse

Protein Name

Poly (U) -binding-splicing factor PUF60

Gene Name URL

PUF60

CAS Number

9007-83-4

Nucleotide Accession Number

NM_001136033.2

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