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PRMT5 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein arginine methyltransferase 5

Gene Aliases

HSL7, JBP1, SKB1, IBP72, SKB1Hs, HRMT1L5

Gene ID

10419

Accession Number

NP_001034708.1

Reactivity

Human, Rat

Immunogen

Recombinant protein encompassing a sequence within the center region of human PRMT5. The exact sequence is proprietary.

Target

This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Clonality

Monoclonal

Clone

GT3610

Type

Monoclonal Antibody

Applications

IP, WB

Purification

Affinity purified by Protein G.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid

Buffer

PBS

Reconstitution

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Fragment

IgG2a

NCBI Gene Symbol

PRMT5

Host or Source

Mouse

Protein Name

Protein arginine N-methyltransferase 5

Gene Name URL

PRMT5

Nucleotide Accession Number

NM_001039619.2

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