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GLS Antibody

Product Specifications

Gene Name

Glutaminase

Gene Aliases

GAC, GAM, KGA, GLS1, AAD20, DEE71, GDPAG, CASGID, EIEE71

Gene ID

2744

Accession Number

NP_001243239.1

Reactivity

Human, Mouse

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human Glutaminase C. The exact sequence is proprietary.

Target

This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

ICC, IF, IHC-P, IP, WB

Purification

Purified by antigen-affinity chromatography.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

0.5 mg/ml

Format

Liquid

Buffer

1XPBS, 20% Glycerol (pH7) . 0.025% ProClin 300 was added as a preservative.

Reconstitution

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Fragment

IgG

NCBI Gene Symbol

GLS

Host or Source

Rabbit

Protein Name

Glutaminase kidney isoform, mitochondrial

Gene Name URL

GLS

CAS Number

9007-83-4

Nucleotide Accession Number

NM_001256310.1

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