Padnarsertib
Product Specifications
Product Name Alternative
KPT-9274
UNSPSC Description
Padnarsertib (KPT-9274) is an orally bioavailable, dual PAK4/Nicotinamide phosphoribosyltransferase (Nampt) inhibitor, with IC50s of [1][2][3].
Target Antigen
NAMPT; PAK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton;Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PAK4-IN-1.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(C=C1)=CC=C1C2=C(OC(CNC(/C=C/C3=CN=C(N)C=C3)=O)=C4)C4=CC(C5=CC=C(C(N6CCC(F)(F)CC6)=O)C=C5)=C2
Molecular Weight
610.63
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12793/Padnarsertib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12793/Padnarsertib-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
1643913-93-2
Available Sizes
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