Human ALDH2 Protein

<strong>Human ALDH2 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011576_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> ALDH2 protein, Aldehyde dehydrogenase mitochondrial protein, ALDH E2 protein, mitochondrial Acetaldehyde dehydrogenase 2 protein, ALDH-2, Aldehyde dehydrogenase protein, ALDH 2 protein, ALDH 2 protein, ALDH-2 protein, ALDM protein, MGC1806 protein, ALDH 2, Aldehyde dehy_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chen CH, Ferreira JCB, Mochly-Rosen D. ALDH2 and Cardiovascular Disease Adv Exp Med Biol. 2019;1193:53-67._x000D_ 2: Zhao Y, Wang B, Zhang J, He D, Zhang Q, Pan C, Yuan Q, Shi Y, Tang H, Xu F, Wei S, Chen Y. ALDH2 (Aldehyde Dehydrogenase 2) Protects Against Hypoxia-Induced Pulmonary Hypertension Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2303-2319._x000D_ 3: Chen CH, Ferreira JC, Gross ER, Mochly-Rosen D. Targeting aldehyde dehydrogenase 2: new therapeutic opportunities Physiol Rev. 2014 Jan;94(1):1-34._x000D_ 4: Zhong S, Li L, Zhang YL, Zhang L, Lu J, Guo S, Liang N, Ge J, Zhu M, Tao Y, Wu YC, Yin H. Acetaldehyde dehydrogenase 2 interactions with LDLR and AMPK regulate foam cell formation J Clin Invest. 2019 Jan 2;129(1):252-267._x000D_ 5: Wang S, Wang L, Qin X, Turdi S, Sun D, Culver B, Reiter RJ, Wang X, Zhou H, Ren J. ALDH2 contributes to melatonin-induced protection against APP/PS1 mutation-prompted cardiac anomalies through cGAS-STING-TBK1-mediated regulation of mitophagy Signal Transduct Target Ther. 2020 Jul 24;5(1):119._x000D_ 6: Yang K, Ren J, Li X, Wang Z, Xue L, Cui S, Sang W, Xu T, Zhang J, Yu J, Liu Z, Shang H, Pang J, Huang X, Chen Y, Xu F. Prevention of aortic dissection and aneurysm via an ALDH2-mediated switch in vascular smooth muscle cell phenotype Eur Heart J. 2020 Jul 7;41(26):2442-2453._x000D_ 7: Zhang H, Xia Y, Wang F, Luo M, Yang K, Liang S, An S, Wu S, Yang C, Chen D, Xu M, Cai M, To KKW, Fu L. Aldehyde Dehydrogenase 2 Mediates Alcohol-Induced Colorectal Cancer Immune Escape through Stabilizing PD-L1 Expression Adv Sci (Weinh). 2021 Mar 24;8(10):2003404._x000D_ 8: Jin S, Cao Q, Yang F, Zhu H, Xu S, Chen Q, Wang Z, Lin Y, Cinar R, Pawlosky RJ, Zhang Y, Xiong W, Gao B, Koob GF, Lovinger DM, Zhang L. Brain ethanol metabolism by astrocytic ALDH2 drives the behavioural effects of ethanol intoxication Nat Metab. 2021 Mar;3(3):337-351._x000D_ 9: Seo W, Gao Y, He Y, Sun J, Xu H, Feng D, Park SH, Cho YE, Guillot A, Ren T, Wu R, Wang J, Kim SJ, Hwang S, Liangpunsakul S, Yang Y, Niu J, Gao B. ALDH2 deficiency promotes alcohol-associated liver cancer by activating oncogenic pathways via oxidized DNA-enriched extracellular vesicles J Hepatol. 2019 Nov;71(5):1000-1011._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34228649">10: Xu T, Guo J, Wei M, Wang J, Yang K, Pan C, Pang J, Xue L, Yuan Q, Xue M, Zhang J, Sang W, Jiang T, Chen Y, Xu F. Aldehyde dehydrogenase 2 protects against acute kidney injury by regulating autophagy via the Beclin-1 pathway JCI Insight. 2021 Aug 9;6(15):e138183. </a>_x000D_ _x000D_ <strong>Products Related to Human ALDH2 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>