What is the catalog number for MDM2 Antibody?

The catalog number for MDM2 Antibody is OAGA01316-100UL.

What sizes are available for MDM2 Antibody?

MDM2 Antibody is available in the following size(s): 100 µL.

Is MDM2 Antibody in stock?

MDM2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

MDM2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

MDM2 proto-oncogene, E3 ubiquitin protein ligase

Gene Aliases

HDMX, LSKB, hdm2, ACTFS

Gene ID

4193

Reactivity

Human, Mouse

Immunogen

Recombinant protein encompassing a sequence within the center region of human MDM2. The exact sequence is proprietary.

Target

This gene is a target gene of the transcription factor tumor protein p53. The encoded protein is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53, as part of an autoregulatory negative feedback loop. Overexpression of this gene can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein has E3 ubiquitin ligase activity, which targets tumor protein p53 for proteasomal degradation. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. More than 40 different alternatively spliced transcript variants have been isolated from both tumor and normal tissues.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

CHIP, IHC-FFPE, IP, WB

Purification

Purified by antigen-affinity chromatography.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol