BAX Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Apoptosis regulator BAX
Gene Aliases
BCL2L4
Gene ID
581
Accession Number
NP_001278357.1NP_001278360.1NP_004315.1NP_620116.1NP_620118.1NP_620119.2
Reactivity
Mouse
Immunogen
Synthetic peptide corresponding to amino acids 172 to 199 of the Bax-beta protein
Target
Bax-beta is encoded by a 1.5 kb RNA species created by the retention of intron 5 in the bax mRNA transcript. The exon4/intron5 splice junction is evolutionarily conserved and is found in both the human and mouse bax coding regions. The 630 bp intron 5 contributes 60 amino acids to the Bax-beta protein before a stop codon is encountered during translation. Although the Bax-beta protein contains the BH1, BH2, and BH3 domains identical to Bax, it has a unique carboxyl terminus and does not have a hydrophobic transmembrane domain. Bax-beta mRNA has been found in many mouse tissues using RT-PCR. It is found co-expressed with Bax-alpha in lung, stomach, kidney, thymus, lymph node, bone marrow, pancreas, and spleen. Bax-beta mRNA was very abundant in brain and duodenum with almost no Bax-alpha mRNA detected in these tissues
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IP
Purification
Ammonium Sulfate Precipitation
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid// PBS with 0.08% sodium azide
Reconstitution
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
Molecular Weight
21 kDa
Fragment
IgG
NCBI Gene Symbol
BAX
Host or Source
Sheep
Gene Name URL
BAX
Nucleotide Accession Number
NM_001291428.1NM_001291431.1NM_004324.3NM_138761.3NM_138763.3NM_138764.4
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