CYP3A5 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Cytochrome P450 3A5
Gene Aliases
CP35, PCN3, CYPIIIA5, P450PCN3
Gene ID
1577
Accession Number
NP_000768.1NP_001177413.1
Reactivity
Human
Immunogen
Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminus of the human CYP3A5 protein and mouse myeloma Ag8563 cells.
Target
CYP3A genes encode monooxygenases, enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A (cytochrome P450, family 3, subfamily A), the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50% of all clinical drugs. CYP3A members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster consists of four genes: CYP3A43, CYP3A4, CYP3A7 and CYP3A5, and two pseudogenes: CYP3A5P1 and CYP3A5P2. The CYP3A cluster maps to gene locus 7q21.3-q22.1.
Clonality
Monoclonal
Clone
F18 P3 B6
Type
Monoclonal Antibody
Applications
WB, IHC
Purification
Protein A/G Chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid.// PBS with 0.08% sodium azide
Reconstitution
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles. Products are stable for one year from purchase when stored properly.
Molecular Weight
57 kDa
Fragment
IgG1
NCBI Gene Symbol
CYP3A5
Host or Source
Mouse
Gene Name URL
CYP3A5
Nucleotide Accession Number
NM_000777.4NM_001190484.2
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