SNAP25 Antibody
SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that plays an essential role in synaptic vesicle fusion and exocytosis. It is involved in the molecular regulation of neurotransmitter release. It is thought to play an important role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. SNAP25 exists as two alternatively spliced isoforms, SNAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells. These two isoforms differ by 9 amino acids in the central portion of the protein.
Product Specifications
CAS Number
9007-83-4
Reactivity
Human, Mouse, Rat, Monkey, Chicken, Cow
Immunogen
Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with rat brain synaptosomal membranes and mouse NS1 cells.
Clonality
Monoclonal
Clone
S-7B8
Type
Monoclonal Antibody
Source
Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with rat brain synaptosomal membranes and mouse NS1 cells.
Applications
WB, IHC
Purification
Protein A/G Chromatography
Assay Protocol
Concentration
Varies by lot. See vial for concentration.
Format
Liquid// PBS with 0.08% sodium azide
Reconstitution
Product should be stored at -20° C. Aliquot to avoid freeze/thaw cycles
Fragment
IgG1
NCBI Gene Symbol
SNAP25
Host or Source
Mouse
Gene Name URL
SNAP25
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