LAT2 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Linker for activation of T cells family, member 2
Gene Aliases
AW125574; LAB; linker for activation of B-cells; linker for activation of T-cells family member 2; membrane-associated adapter molecule; non-T cell activation linker; Non-T-cell activation linker; NTAL; Wbsc; Wbscr; Wbscr15; Wbscr5; williams-Beuren syndrome chromosomal region 15 protein homolog; Williams-Beuren syndrome chromosome region 5 homolog; WSCR5.
Gene ID
56743
Accession Number
NP_054865.2NP_115852.1NP_115853.2
Reactivity
Human|Mouse
Immunogen
Recombinant cytoplasmic domain (aa 91-243) of human NTAL.
Target
Involved in FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor) -mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I) -mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Clonality
Monoclonal
Clone
NAP-07
Conjugation
R-PE
Type
Monoclonal Antibody
Applications
Flow cytometry
Purification
Purified by size-exclusion chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
0.1 mg/ml
Format
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Buffer
The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Reconstitution
2°C to 8°C
Fragment
IgG1
Specificity
The antibody NAP-07 reacts with Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25 - 30 kDa transmembrane adaptor protein present in membrane microdomains (rafts) of B lymphocytes, NK cells and myeloid cells.
NCBI Gene Symbol
Lat2
Host or Source
Mouse
Protein Name
Linker for activation of T-cells family member 2
Gene Name URL
Lat2
Nucleotide Accession Number
NM_014146.3NM_032463.2NM_032464.2
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