CYM-5541
CYM-5541 (ML249) is an selective and allosteric S1P3 receptor agonist with an EC50 between 72 and 132 nM.
Product Specifications
CAS Number
945128-26-7
Product Name Alternative
ML249
UNSPSC
12352005
Hazard Statement
H302
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/CYM-5541.html
Concentration
10mM
Purity
99.65
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(C1=NOC(C2CC2)=C1)N(C3CCCCC3)C4CCCCC4
Molecular Formula
C19H28N2O2
Molecular Weight
316.44
Precautions
H302
References & Citations
[1]Jo E, et al. Novel selective allosteric and bitopic ligands for the S1P (3) receptor. ACS Chem Biol. 2012 Dec 21;7 (12) :1975-83.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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